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Stop-Smoking Drug Might Work For Drinkers, Too
March 5, 2009

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Research Summary

Varenicline is already sold as a stop-smoking drug under the name Chantix, but now researchers say the drug also may help heavy drinkers cut down on their alcohol consumption,  Medical News Today reported March 3.

Yale School of Medicine researchers found that heavy-drinking smokers given varenicline were less likely to drink than those given a placebo, and also reported feeling fewer cravings for alcohol and less of a feeling of intoxication when they did drink. They also were more likely to decline when offered a drink than those in the placebo group.

The study found that 80 percent of the varenicline group did not drink at all during the research period, compared to 30 percent of the placebo group.

Researchers noted that combining varenicline with alcohol did not produce any major side-effects, which could make it a safer alternative to naltrexone, which is metabolized by the liver.

"We anticipate that the results of this preliminary study will trigger clinical trials of varenicline as a primary treatment for alcohol use disorders, and as a potential dual treatment for alcohol and tobacco use disorders," said researcher Sherry McKee.

The study was published online in the journal Biological Psychiatry.

COMMENTS ON THIS ARTICLE:

Posted by Luis Lozano on 06 Mar 09 01:54 PM EST
Using one drug to quit another just does not make sense. None of these therapies do anything to address the root causes of alcoholism or drug addiction and in the long run their is no proof that they work. It is just another attempt by the drug companies to market their products to desperate people looking for real help.

Posted by doogiem on 06 Mar 09 02:46 PM EST
Luis, Your reaction to this article seems pretty rigid, black and white, and limiting. Lighten up, dude! Are you a conspiracy theorist?!?! ;^) Who said anything about "root causes"?!?!Using Valium (one drug -- to help with withdrawals) does indeed help many alcoholics in their attempt to quit alochol (another drug).

Posted by Melissa on 06 Mar 09 10:38 PM EST
I don't care how my patients quit as long as they quit smoking or abusing alcohol or drugs. I do NOT work for Pfizer. I have NO financial ties to Pfizer. I do not accept any renumeration from Pfizer. As a physician, I'm grateful for Chantix. It's the only smoking cessation drug that works. As predicted, the great conspiracy has begun to try to paint this medication as dangerous compound. Brain mets, heart attacks, oxygen dependancy, tongue excisions, lung cancers, tracheostomies.......those all sound pretty dangerous to me. I always tell my smoking patients who are "afraid" to start chantix to bring me a pill and I'll swallow the first one with them. I WOULD NOT, however, smoke a pack of cigarettes. That would be very frightening indeed.

Posted by Dean L. Lett on 07 Mar 09 02:47 AM EST
Yes, and Valium can kill you. And what happens Melissa when your left hand falls off twenty years from now because of effects that may be long term and not being caught in short term trials? I think Luis is right to be apprehensive.

Posted by Maureen on 07 Mar 09 12:31 PM EST
I have been on Chantix for three weeks and have gone from smoking a pack a day to three cigarettes. My prescription is for a three month period,but I believe by the time I finish my second month of Chantix I won't need the third month. Remember- this is not a drug you will take for life. Two or three months of one drug might just save your life. Try it- it works.

Posted by mark on 08 Mar 09 12:48 PM EDT
key is wether a short term treatment with chantix stops the desire to smoke forever or for a very long time at a minimum. s for a short duration only then it's not worth it, it seems to me. If one prescription drug can stop a dangerous addiction or lessen withdrawal symptoms(as methidone does for heroin or other types of drugs addiction)then it is very worthwile.The withdrawal symptoms are so bad that you can die; ask any addict and they will overwhelmingly agree that methidone is very helpful. The end result is to slowly reduce the amopunt of methidone so that the patient can be free of any addiction.Many/most hardcore addicts would die without the option of methidone.I am not an advocate of p[rescrition med. in general, in fact I think they arte abused in todays society are are harming many people including myself.I like to keep an open mind always, and once a person becomes addicted the options are limited so any option is better than none.

Posted by carolyn on 08 Mar 09 04:54 PM EDT
Any drug can be harmful or even kill you if it's misused, but i'm for anything that will help a person get through withdrawal symptoms. A few years ago i suffered seizures and fainting spells after being taken off morphine, Percocet, and Ativan abruptly. My incompetent doctor refused to give me any benzodiazepines to help me get through the withdrawal syndrome. The reason he gave for this was, "I don't want you to be a junkie." I almost died because of this doctor's ignorance. A little Ativan or Valium would have saved me a lot of suffering during that time and i would NOT have needed to be a "junkie" by taking it perpetually. Some drugs when used CAREFULLY are beneficial.

Posted by mirn81 on 09 Mar 09 05:25 PM EDT
Luis, you sound like you either subscribe to scientology views or are employed by Narconon. I have seen numerous smokers who successfully kicked the habit with the short-term (3 months or less) use of Chantix. And if it works for alcohol addiction, so much the better. And I am also not affiliated with Pfizer--just a nurse who has seen positive results. You have so much more to learn about addiction/dependence on drugs--you should really take a class. Look at what Mark went through due to the ignorance of his physician on the same subject. He would not have experienced life-threatening side effects with the short-term, tapering doses of benzodiazepines. And the same for heroin withdrawl. Methadone is essential in helping someone withdraw from heroin without their lives being put in danger. It just takes a skilled practicioner, educated in the short-term, tapering use of these drugs to effect a change. Even many physicians are not educated in substance abuse/treatment. But before you expound your views further, you really should take a free class in substance abuse treatment.

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