Medication Key to Alcoholism Treatment Success, Study SuggestsJune 30, 2008
Research Summary
Alcohol-dependent individuals who consistently took prescribed medications to prevent withdrawal symptoms and craving had better treatment outcomes than those who didn't take their medication, even among patients receiving behavioral counseling, researchers say.
HealthDay News reported June 20 that data from the National Institute on Alcohol Abuse and Alcoholism's Combine study found that those patients who adhered to the medication regimen for naltrexone or acamprosate as well as taking part in medical-management (MM) or combined behavioral intervention (CBI) programs had more abstinent days and avoided heavy drinking more successfully than those who didn't take their prescribed drugs as ordered.
"High medication adherents fared better than low medication adherents across all combinations of behavioral and pharmacological treatment conditions," said researcher Allen Zweben of Columbia University.
The researchers also reported that CBI seemed to help even patients who took a placebo, but did not appear to affect relapse rates among naltrexone patients who didn't take their medications.
"Both of these behavioral treatments (CBI and MM) performed equally as well with regard to treatment adherence and medication adherence rates," Zweben said, adding that the low-intensity MM combined with naltrexone could be used to help a large percentage of patients with alcohol dependency.
The study was published online in the journal Alcoholism: Clinical and Experimental Research and will appear in the September 2008 print issue.

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