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Drug Offers Effective Alternative Treatment for Heroin Addicts
October 20, 2008

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Research Summary

The latest research from the North American Opiate Medication Initiative (NAOMI) suggests that hydromorphone -- an opiate found in prescription cough medicines like Dilaudid -- is more effective than methadone in reducing rates of illicit drug use and improving abstinence retention rates among opiate addicts, the National Post reported Oct. 18.

NAOMI researchers prescribed medical-grade heroin, methadone and hydromorphone to individuals addicted to heroin. After three years, the study found that those both the heroin-maintenance and hydromorphone group had better outcomes than the methadone group. Hydromorphone was so effective that almost all the participants in the group believed they were being given heroin.

"To be perfectly frank, there is a stigma attached to heroin. That would make [hydromorphone] particularly attractive in places where the concept of using heroin would be untenable as a public policy," said Martin Schechter, lead investigator of the project and director of the University of British Columbia School of Population and Public Health.

Schechter said that while there would be challenges to using hydromorphone to treat addiction, the hurdles would be small compared to getting prescription heroin approved. The researchers are already in negotiations with the Vancouver Coastal Health Authority about making the NAOMI research center into a permanent drug-treatment clinic that would offer methadone and hydromorphone maintenance.

This article summarizes an external report or press release on research published in a scientific journal. When available, links to the sources are provided above.

COMMENTS ON THIS ARTICLE:

Posted by drpasser on 21 Oct 08 08:20 AM EDT
I run a detox clinic. This is not a good idea. Suboxone is excellent. One cannot overdose on Suboxone. Hydromorphone could be deadly. Suboxone reverses the Opiate Receptors. Hydromorphone would not. Bad idea. The problem is that Suboxone is not used in Canada, but it should be.

Posted by G. Chappell on 21 Oct 08 08:39 AM EDT
Replacement therapy needs to be effective and if it is more effective than others it sounds promissing.

Posted by Jim Ray on 21 Oct 08 08:55 AM EDT
Insanity

Posted by Robin on 21 Oct 08 09:44 AM EDT
Dilaudid compared to methadone (injection as opposed to oral) will of course retain in treatment if methadone doses are inadequate... need much more data to make the comparison valid.

Posted by John from Oceanside on 21 Oct 08 11:00 AM EDT
Yaa I'd tay in treatment if they gave me free drugs!!! How is this treatment?

Posted by b rubin on 21 Oct 08 11:37 AM EDT
suboxone is without a doubt the best alternative for heroin use.

Posted by JMotterotz on 21 Oct 08 11:48 AM EDT
It's very interesting and encouraging to see that field of addiction medicine is finally embracing the premise of progress-not-perfection when it comes to improving the lives of addicts, their families and the public at large. Is it realistic to assume that the majority of heroin addicts are going to recover using the Minnesota model exclusively? Do we insist that heart patients achieve perfect health or the diabetic uphold all the tenets of perfect health. How we allowed ourselves to become backed into a corner of idealism and perfection at all costs(even the LIFE of the patient/addict)is something to ponder as we leave this type of thinking behind. M.A.T. and Assisted Recovery in general is a breath a fresh air in a field of medicine that for too long has relegated its authority over to self-help practitioners who rightfully concentrate on singleness of purpose rather than taking a adjunct position when it comes to designing a individualized treatment plan for the addict. The sooner the one-size-fits-all model of recovery fades away the better off we will all be.

Posted by M Branch on 21 Oct 08 12:29 PM EDT
While I mostly concur with the above posting of J Motterotz, I would like to add that the use of hydromorphone, is substituting heroin, plain and simple. Suboxone studies appear to be promising. But a drug is a drug is a drug... and the use of any opiates for an addict striving for recovery is not an option. Addiction is a family disease, and for the addict, alcholic to attain and maintain sobriety, the family must willingly embrace counseling aspects of treatment as well as the addict.

Posted by j.Lundin-Martinez on 21 Oct 08 01:40 PM EDT
This is an interesting concept and I welcome research for alternatives to methadone. What I find really interesting is that all of the stigmas around medication assisted therapy are still prevalent as are many of the misconception regarding treatment.

Posted by P. Kaplan on 21 Oct 08 02:51 PM EDT
I used to believe in the abstinence-only model. Then along came AIDS. Dead patients can't achieve abstinence (well, death is one kind of abstinence but not an acceptable goal for treatment). "Treatment professionals" who make comments like 'suboxone is the best alternative' are misguided. It may be best for them. It may be best for many. What we need are "treatment facilitators" who will help addicts along the path to a better quality of life, whether or not it's the path they would choose for themselves. The fact that we're still arguing about this after 90 years should be proof that there is no simple answer to heroin (or other) addiction.

Posted by joda on 24 Oct 08 04:01 PM EDT
Medication-Assisted-Treatment uses some very effective tools like suboxone, methadone, and naltrexone to go along with counseling, case management, group therapy, job assistance and alike, depending on the what fits that particular case. One thing I suggest is that addiction medicine take a new look into the old Southern Cure for die-hard alcoholics who were prescribed morphine to end there addiction to booze. Many of us have witnessed advanced alcoholics put down the bottle almost instantaneously when heroin was given. It ameliorates acute alcohol withdrawal and supplants the alcohol appetite literally overnight. It is nothing short of miracleous. The rub here of course is the ex-alchy becomes a new junkie. However we know how to treat heroin addiction much better than we do end-stage and severe cases of alcoholism.

Posted by archiecat on 27 Oct 08 03:39 PM EDT
Suboxone in a treatment setting can be used as a detox medication, as opposed to using it as a maintenance tool in a drug replacement program. It is a tool that can be used for different purposes (detox or maintenance) in different settings. I accept in principle the idea of harm reduction, but most folks who come into our facility need to become clean and sober. Relapse threatens the very benifit they are using to be in treatment. Many of our people only get one or two treatment episode per lifetime if they are fortunate. They need and want a way to get off drugs and back to work ASAP. There are those who have been on maintenance for years and need an effective way to get off Methodone. There are not enough options. We are overwhelmed trying to provide individualized treatment to the many and varied clients in our program, let alone our county.

Posted by doktorlisa on 30 Oct 08 08:35 AM EDT
Reduced illicit opiate use is important but what about quality of life? I would suspect those on hydromorph maintenance might be feeling too much euphoria and are not able to return to optional occupational and social functioning.

Posted by baiks on 24 Feb 09 12:09 PM EST
Hydromorphone (Dilaudid) is known as "drug store heroin". Dilaudid is considered by many users to be superior to heroin because it is pure and unadulterated. Heroin is known as "junk" because it is cut to varying degrees with different substances. Dilaudid is expensive. A typical dose is 4mg. On the street Dilaudid sells for 5 to 10 dollars per milligram. Heroin is a lot cheaper. Therefore, more people use heroin. The article states that "hydromorphone was so effective that almost all the participants in the group believed they were given heroin" - of course they did - they were basically given heroin. This study is beyond ridiculous and shows that the researchers are ignorant regarding this issue.

Posted by joda on 03 Mar 09 07:27 PM EST
Really? I think the researchers knew exactly what they were purporting. Many are under the false assumption that abstinence via the Minnesota Model is the defintion of success regarding treatment outcomes even when less than 5% of alcoholics achieve sobriety using it. The number is somewhere closer to .05 to 1% for junk addicts; minus thousands of junkies who die every year because they can't achieve abstinence using the "A/A way" which was never supposed to treat junkies anyway. Our learning becomes impeded when we are no longer led by experience but by ideas; by what should be rather than what is. This x-junkie--now methadone "addict" of ten years with a career, job and family--says: let's save lives, not ideas.

Posted by Lucy on 06 Mar 09 05:33 AM EST
The best treatment against heroin addiction is the treatment with Naltrexona but first you must do a procedure called ANR(Accelerated Neuro-Regulation) that cleans your extra receptors from the brain developed because of the Heroin consumption and blocked them. The treatment is now doing in Romania (visit the site www.forad.ro) and the rate of relapse is 80%. In only think you must do every day for one year is to take one pill of Naltrexona when you open your eyes.

Posted by Christopher Cook on 06 Mar 09 08:45 AM EST
I wonder why the addicts stayed in treatment longer? Here's a thought, maybe all this suggests is hydromorphone gives as good a rush as heroin.What respectable researcher performs this unbelievable research. Did it ever occur to anyone that the addicts are staying in treatment longer, BECAUSE THEY ARE GETTING HIGH? Come on people, someone has to be smarter than this. We have abandoned common sense.

Posted by parrothead on 26 Apr 09 12:12 PM EDT
First off: all of you 12 steppers,and other "experts" on medically assisted treatment, what gives you the right to tell me what to put in my own body? Are you my parents? Have any of you studied the programs in place in Switzerland, England, or Germany? Can you explain why you continue to ignore the obvious success rates they exhibit? Lastly, will you never tire of repeating the same tired arguments you heard at your twelve steppin meeting? Please...THINK FOR YOURSELF!

Posted by brenden E. on 14 May 09 04:47 PM EDT
First off, as a recovring heroin addict myself, the idea of giving heroin addicts dilaudid(hydromorphone) IS INSANE. Not only is dilaudid only a substitute for smack, its better in many ways in my opinion(pleasure wise) It is a very sought after drug in the heroin world. Now, that being said, I myself got off of heroin with suboxone treatment. It is not an alternative to heroin use, it is a way to kick it altogether. It is simply a miracle drug, it is an opiate, but a shorter acting opiate then methadone. Therefore the withdrawl is much lighter and easier to kick. The way it works is you wait until the patient enters into withdrawl from heroin, 14-24 hours after last use, then start them on suboxone, sublingual. They market subutex, which is pure buprenorphine sublingual, but can be injected, i know from experience. Suboxone has naltrexone in it, an antagonist to block all other opiates and take control of the receptors in the brain. anyway, you stay on it for 8-10 days on varied doses going high to low on cycles and for the last 2 days decresing, for a rapid taper. All the while feeling no withdrawl or pleasurable effect, then off the suboxone and a VERY mild withdrawl and you just kciked heroin.

Posted by breden e on 14 May 09 05:03 PM EDT
I hope the medical community all realizes what a horrible idea this is. And they also need to make suboxone AFFORDABLE to the general public the way methadone is. Methadone is a trap, I know people who take it and have been taking it for 8 years EVERYDAY. Its a substitute, not a way out by ANY means. Its governments control of addicts in my opinion. Another way to make money on the sick and dying. I tried to get on suboxone and doctors wanted 1000's of dollars up front. I had to get so far gone that I overdosed and was legally dead from IV heroin. ONLY THEN did they commit me to an asylum and detox me with suboxone for free because i was a danger to my own life due to my heroin habbit. If I hadnt of od'd and gotten free suboxone at detox I WOULD NOT BE SOBER TODAY. NO WAY IN HELL. So suboxone is the future of heroin addiction treatment, hands down. Many people out there have similar stories to mine. Do your homework people. And dont think you understand it if you havent lived it, because you dont. not by any means. And ny the way im only 21 years old and have 6 months clean and counting. Suboxone and and a 12-step recovery program are the only way in MY experience. Thanks for reading!

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