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In Large Doses, Red Wine Ingredient Shows Health Benefit
November 7, 2006

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Research Summary

A new study says that a chemical found in red wine can promote health and long life even in the face of a high-fat diet, but you'd have to drink many gallons of wine to match the doses given to lab animals.

The Associated Press reported Nov. 7 that researchers extracted resveratrol -- a substance made by stressed plants and found in red grape skins -- from red wine and gave massive doses to mice on a high-fat diet. In what were termed "spectacular" findings, the study showed that the mice given resveratrol lived longer and healthier lives than those who consumed high amounts of fat but did not get resveratrol.

The mice given resveratrol had lower levels of diabetes, liver problems, and other conditions related to obesity, researchers from the Harvard Medical School and National Institute of Aging said. The resveratrol mice were 31 percent less likely to die from fat-related conditions than the untreated mice, and did not appear to suffer the organ damage expected from a high-fat diet.

To match the dose of resveratol given the lab mice, a human would need to drink over 750 bottles of wine a day, according to the New York Times report on the same study.

The study was published Nov. 1 in the online version of the journal Nature

Reference:
Baur, J.A., et al. (2006) Resveratrol improves health and survival of mice on a high-calorie diet. Nature, advance online publication 11/01/2006, doi:10.1038/nature05354.

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