Bupropion Helps Meth Addicts, Study FindsNovember 28, 2005
Research Summary
A small study by researchers at UCLA found that methamphetamine users given the antidepressant bupropion (Wellbutrin) reported fewer cravings for the stimulant, the Los Angeles Times reported Nov. 23. Test subjects given bupropion, shown a video of people using meth, reported their craving as negative 8 on a scale with a baseline of zero. The 10 members of the placebo group rated their craving as plus 10.
The bupropion patients also experienced a less intense high after taking methamphetamine, researchers led by Thomas F. Newton reported. Study members given bupropion rated their "high" at 28 on a 70-point scale, compared to 48 for meth users.
The "study is provocative and potentially promising," said Columbia University psychiatry professor and drug expert Eric Collins. UCLA's Richard Rawson, who led the study, said another study involving 120 subjects would be presented at a National Institute on Drug Abuse conference in December.
The research was published in the journal Neuropsychopharmacology.
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