Researchers at the Commonwealth Scientific and Industrial Research Organization (CSIRO) found that the mutant poppy plant, called top1, blocks the production of codeine, morphine, and other analgesics.

"The new poppy variation can produce, at very high yield, thebaine and oripavine (rather than morphine and codeine). These two alkaloids are preferred starting points for the subsequent manufacture of a new generation of powerful analgesics," said study author Dr. Philip Larkin. "We are already using this knowledge to produce other designer changes in poppies to serve human pharmaceutical needs better."

"Buprenorphine and other derivatives of thebaine and oripavine, such as naltrexone, are also playing a major role in treatment of opiate addiction," Larkin added.

The morphine-free poppy was discovered in Tasmania, Australia, in 1995.

The study's findings are published in the Sept. 22 issue of the science journal Nature.

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