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New Version of Naltrexone Treats Alcohol Addiction in Men
March 8, 2004

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Research Summary

An injectable version of the anti-addiction medication Naltrexone is showing some promise in treating male alcoholics, Michigan's WILX TV-10 reported March 3.

Naltrexone blocks brain chemicals that activate the euphoria obtained from alcohol and other drug use. Previous studies evaluating the pill form of Naltrexone found that it only worked if individuals remembered to take it every day. In addition, many patients stopped taking the medication after a couple of months because it didn't have a strong enough effect in stopping their cravings.

The injectable version, on the other hand, lasts an entire month. A study of 600 men and women found that it reduced heavy drinking among men by nearly 50 percent compared to a placebo.

But the Naltrexone injection had no effect on women. Researchers are conducting a larger study to determine why.

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