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DrugScreening.org


 
Gene Tied to Nicotine Addiction
December 7, 2006

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News Summary

The gene CYP2A6, which helps produce an enzyme that breaks down nicotine, is more active among most heavy smokers, according to researchers at Japan's Osaka University.

Reuters reported Dec. 6 that researchers examined 300 current and former smokers and found that 70 percent of those with overactive versions of the gene were highly addicted to nicotine. Among less-addicted smokers, only 40 percent had the CYP2A6 gene.

Determining the genotype of smokers could help doctors tailor cessation programs to best suit individual needs, the researchers said. 

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